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Synthace

Synthace

Synthace is a software company based out of London, UK, building automation software that gives biologists the ability to control and analyze the performance of lab hardware.

Synthace is a software company, founded in 2011 by Sean Ward, Markus Gershater, and Christopher Grant. Synthace builds software tools that work with scientists and their lab hardware with the goal of improving lab productivity. Their software allows scientists to communicate with their lab hardware in a way that lets them plan, execute, and repeat biological experiments.

Products and services
Antha

Antha is a cloud based operating platform made by Synthace. Antha is made to help scientists design, execute, analyze, and replicate aspects of their lab work. The company claims that Antha can produce a 100-fold improvement in lab productivity, a 50% reduction in the time it takes to generate internal vector constructions, a 33% reduction in the cost of running experiments, and an increase in enzymatic activity by 100X compared to pre-Antha platforms. Below you can find brief descriptions of specific services Antha software offers to users which are: construct assembly, data integration, and liquid handling.

Antha helps scientists build type IIS construct assemblies by automating and reproducing the workflow of lab hardware involved in construct assembly. This automation is made possible through the use of liquid handling robots that can perform lab tasks involved in construct assembly. Antha software allows work flows of different lab hardware systems to work together, such as construct assembly, transformation, and plating-out. These process can be automated, reproduced, and customized to the needs of each laboratory. Antha software keeps track of and organizes information generated by lab hardware, producing clean data sets for scientists to work with, and offers online and offline visualization tools that can be easily shared with other users. Antha software is integrated with: Azure, GitHub, Python, Jupyter, Pandas, matplotlib, numpy, and jmp.

Funding
Seed round 1

On April 12th, 2013 Synthace raised $900,000 in funding from Sharaf Yamani, Sami Mikati, Michail Eleftheriou, John Anthony Knight, and David Lucas.

Seed round 2

Synthace raised $2,000,000 in seed funding on September 24th, 2013. Investors include Sofinnova Partners, Innovative UK, and Keith Willey.

Seed round 3

On December 14th, 2014 Synthace announced that it raised $3,500,000 in seed funding from Sofinnova Partners, SOSventures, Bioeconomy Capital, and the Rainbow Seed Fund.

Series A

Synthace completed its series A funding round on September 19th, 2017. They received $9,600,000 in funding from White Cloud Capital (Luminous Ventures), Sofinnova Partners, SOSventures, Bioeconomy Capital, Amadeus Capital, and 11.2 Capital.

Partnerships
Cambridge Consultants

In April 2017, Synthace announced a partnership with Cambridge Consultants. The partnership is focused on promoting the adoption and improvement of Synthace's Antha software. Cambridge Consultants is offering a consulting service to help companies get the most out of Antha by helping implement features of Antha in their labs such as; process development, protocol development, custom equipment development, and automation integration. The partnership is focused on promoting the adoption and improvement of Synthace's Antha software. Cambridge Consultants is offering a consulting service to help companies get the most out of Antha by helping implement features of Antha in their labs, such as process development, protocol development, custom equipment development, and automation integration.

Dow AgroSciences LLC

Dow AgroSciences, a subsidiary of the Dow Chemical Company, announced it will begin collaborating with Synthace in October, 2015. The partnership is a research collaboration effort between the two companies to improve crop protection. Dow AgroSciences will be using Antha with their own fermentation technology to develop new microbial strains capable of producing desired chemicals. By using Antha, Dow ArgoSciences hopes to develop new products faster and cheaper for farmers that will help prevent pest infestation and control disease in ways that increase crop yields.

Gilson

Gilson and Synthace announced their partnership in April, 2018. The companies pledged to begin working together to merge Antha with Gilson's liquid handling platform PIPETMAX. They are working on creating a visual drag-and-drop system that will allow the people using PIPETMAX to customize their workflows. The software system will be able to be used remotely for programming many tasks of the PIPETMAX, such as transfers, dilutions, master mix preparation, and provide data management.

Merck & Co

In November 2015, Merck and Synthace announced they will be working together to optimize their Antha software to become a better bio-manufacturing platform. Synthace is hoping to use the large amount of experience Merck has in manufacturing pharmaceuticals to improve the functionality of their Antha software.

Microsoft

On April 6th, 2016 a partnership was announced between Microsoft and Synthace. The partnership is through Microsofts BizSpark Plus program, and gives Synthace the ability to use the Azure cloud analytics, cognitive services, and machine learning capabilities of Microsoft to improve Antha and Synthace. The partnership is through Microsofts BizSpark Plus program, and gives Synthace the ability to use the Azure cloud analytics, cognitive services, and machine learning capabilities of Microsoft to improve Antha.

Oxford Biomedica, Cell and Gene Therapy Catapult, and Stratophase

Oxford Biomedica is the lead partner in this partnership of Synthace, Cell and Gene Therapy Catapult, and Stratophase. The partnerships with these companies was announced in August, 2017 and is focused on developing more efficient cell and gene manufacturing systems and technologies.

Patents

Patent description
Inventors
Status
Date
App/pub number

Michael Ian Sadowski, Sean Michael Ward

Application

2017-01-12

US20170011170A1

Markus Christian Gershater, Sean Michael Ward, Michael Ian Sadowski, Christopher Richard Grant

Application

2017-01-12

US20170011045A1

Timeline

November 16, 2021
Synthace raises a $35,000,000 series C round.
July 13, 2021
Software Startups Aim to Automate Bio Labs - IEEE Spectrum
December 2018
Synthace raises a $25,600,000 series B round from Horizons Ventures, Luminous Ventures and SOSV.
September 19, 2017
Series A Funding Round

Synthace completes its series A funding round on Septmber 19th, 2017, receiving $9,600,000 in funding from White Cloud Capital, Sofinnova Partners, SOSventures, Bioeconomy Capital, Amadeus Capital, and 11.2 Capital.

September 2017
Synthace raises a $9,600,000 series A round from 11.2 Capital, Amadeus Capital Partners, Bioeconomy Capital, Luminous Ventures, SOSV, Sofinnova Partners, UK Innovation & Science Seed Fund and White Cloud Capital.
August 1, 2017
Partnership: Oxford Biomedica, Cell and Gene Therapy Catapult, and Stratophase

Oxford Biomedica is the lead partner in this partnership between Synthace, Cell and Gene Therapy Catapult, and Stratophase. The partnerships between these companies was announced in August, 2017 and is focused on developing more efficient cell and gene manufacturing systems and technologies.

April 6, 2016
Partnership: Microsoft

On April 6th, 2016 a partnership was announced between Microsoft and Synthace. The partnership is through Microsofts BizSpark Plus program, and gives Synthace the ability to use the Azure cloud analytics, cognitive services, and machine learning capabilities of Microsoft to improve Antha.

November 1, 2015
Partnership: Merck & Co

In November 2015, Merck and Synthace announced they will be working together to optimize their Antha software to become a better bio-manufacturing platform. Synthace is hoping to use the large amount of experience Merck has manufacturing pharmaceuticals to improve the functionality of their Antha software.

October 1, 2015
Partnership: Dow AgroSciences LLC

Dow AgroSciences is a subsidiary of the Dow Chemical Company that announced it will begin collaborating with Synthace in October, 2015. The partnership is a research collaboration effort between the two companies to improve crop protection. Dow AgroSciences will be using Antha with their own fermentation technology to develop new microbial strains capable of producing desired chemicals. By using Antha, Dow ArgoSciences hopes to develop new products faster and cheaper for farmers that will help prevent pest infestation and control disease in ways that increase crop yields.

February 2015
Synthace raises a $3,080,000 venture round from Bioeconomy Capital, Sofinnova Partners and UK Innovation & Science Seed Fund.

Funding Rounds

Patents

Further Resources

Title
Author
Link
Type
Date

Antha OS Documentation

Synthace

​Antha: a platform for engineering biology

Daniela Quaglia

Dr. Xander Anderson on Antha (RebelBioFuture)

March 16, 2017

How synthetic biology is exploring biological complexity: Sean Ward at TEDxVilnius

February 25, 2014

Leaf LIMS: A flexible laboratory information management system with a synthetic biology focus

Thomas Craig, Richard Holland, Rosalinda D’Amore, James Johnson, Hannah V McCue, Anthony West, Valentin Zulkower, Hille Tekotte, Yizhi Cai, Daniel Swan, Robert P Davey, Christiane Hertz-Fowler, Anthony Hall, Mark Caddick

Academic paper

News

Search on Google News
Search on Bing News
Title
Author
Date
Publisher
Description
BioSpace
May 19, 2021
BioSpace
Synthace Ltd, the cloud-based software platform for automating biological R&D, announced the appointment of Guy Levy-Yurista as Chief Executive Officer and Board Member to guide Synthace through its next stage of growth.
FierceBiotech Staff
November 5, 2020
FierceBiotech
Ipsen has teamed up with Synthace to ramp up the development of new treatments targeting secretion in a wide range of diseases, including oncology, endocrinology, pain management and rare disease. The company is also exploring the use of these drugs in regenerative medicine.

References

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